Could a simple steroid rinse during back surgery cut pain?
NCT ID NCT04182997
First seen Jun 06, 2026 · Last updated Jun 23, 2026 · Updated 5 times
Summary
This study tests whether rinsing the surgical area with a steroid (dexamethasone) during herniated disc surgery can lower pain and disability afterward. About 200 adults with a single-level lumbar disc herniation who have not improved with rest or therapy will be randomly assigned to get the steroid rinse or a plain saline rinse. Researchers will compare pain scores and function in the days after surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Missouri Orthopaedic Institute
RECRUITINGColumbia, Missouri, 65202, United States
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
dexamethasone (a steroid)
What this could lead to
If it works, this could give surgeons a simple way to lower pain and speed recovery after disc surgery.
What could go wrong
This is a small, early-phase trial. The steroid may not reduce pain more than a placebo rinse, and there is a small risk of infection or other complications.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.