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New vaccine combo tackles Hard-to-Treat cancers

NCT ID NCT05631899

First seen Jan 10, 2026 · Last updated May 22, 2026 · Updated 20 times

Summary

This early-phase trial tests a custom-made vaccine that uses a patient's own immune cells to target specific cancer markers (EphA2 and KRAS mutations). The vaccine is given together with two immunotherapy drugs (anti-PD-1 and anti-CTLA4) to boost the immune system's attack on advanced or metastatic solid tumors. The study enrolls up to 9 adults whose cancers have not responded to standard treatments, and aims to check safety, tumor shrinkage, and immune response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Biotherapeutic Department of Chinsese PLA Gereral Hospital

    Beijing, Beijing Municipality, 100853, China

Conditions

Explore the condition pages connected to this study.