New pill tested to ease sickle cell pain and crises
NCT ID NCT05861453
Summary
This study is testing an oral capsule called epeleuton in adults with sickle cell disease. It aims to see how the drug behaves in the body, if it is safe, and if it can improve blood health and reduce painful crises over 16 weeks of treatment. The goal is to find a new treatment to help manage the disease.
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Contacts and locations
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Locations
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Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta at Arthur M. Blank Hospital
Atlanta, Georgia, 30329, United States
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Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta at Hughes Spalding
Atlanta, Georgia, 30303, United States
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Emory University - Georgia Comprehensive Sickle Cell Center
Atlanta, Georgia, 30303, United States
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Jacobi Medical Center
The Bronx, New York, 10461, United States
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Kaiser Permanente Mid-Atlantic States
Largo, Maryland, 20774, United States
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Karmanos Cancer Institute
Detroit, Michigan, 48201, United States
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Medstar Health
Washington D.C., District of Columbia, 20010, United States
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New England Sickle Cell Institute, UConn Health
Farmington, Connecticut, 06030-1163, United States
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Newark Beth Israel Medical Center
Newark, New Jersey, 07112, United States
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Robert Wood Johnson Medical School Rutgers
New Brunswick, New Jersey, 08901, United States
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Science 37
Morrisville, North Carolina, 27560, United States
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St Paul's Hospital Hematology/Oncology Research
Vancouver, British Columbia, V6E 1M7, Canada
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The Center for Cancer and Blood Disorders, A Division of American Oncology Partners, PA
Bethesda, Maryland, 20817, United States
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The Johns Hopkins University School of Medicine
Baltimore, Maryland, 21205, United States
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Toronto General Hospital
Toronto, Ontario, M5G 2C4, Canada
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UI Health Sickle Cell Center
Chicago, Illinois, 60612, United States
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UNC Health
Chapel Hill, North Carolina, 27517, United States
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University of Alabama at Birmingham (UAB)
Birmingham, Alabama, 35294, United States
Conditions
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