Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New eczema pill shows promise in early trial

NCT ID NCT07298395

Symptom relief Sponsor: Enveda Therapeutics Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 30, 2026 · Updated 2 times

Summary

This study tests whether a new oral drug called ENV-294 can safely reduce eczema severity in adults with moderate-to-severe atopic dermatitis. Sixty participants will take either ENV-294 or a placebo pill daily for 12 weeks. Researchers will measure changes in skin symptoms and track any side effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ENV-294
What this could lead to
If it works, this could point toward a new daily pill to ease eczema symptoms and reduce skin severity.
What could go wrong
This is an early Phase 2 trial with only 60 people. The drug may not work better than placebo, and side effects are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Have chronic atopic dermatitis that was diagnosed at least 12 months prior to the first study visit * Have moderate-to-severe AD at screening and baseline as defined by the following criteria: * A vIGA score of 3 (moderate) or 4 (severe) * EASI score of ≥16 * BSA ≥10% * PP-NRS score of ≥4 * Have had either a poor response or intolerance to topical treatments for atopic dermatitis (such as corticosteroids) within the past 6 months * Use a bland moisturizer at least daily Exclusion Criteria: * Current or recurrent medical conditions that could affect the study drug or study assessments * Any illness that could impact participant safety or active infections * Ongoing skin condition or large tattoos that would interfere with clinical assessment * Clinically significant skin infection requiring treatment * Clinically significant abnormal laboratory assessments at screening

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Atopic dermatitis (AD) are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

atopic eczema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atopic dermatitis (AD)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    32 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Enveda Investigative Site

    RECRUITING

    Birmingham, Alabama, 35244, United States

  • Enveda Investigative Site

    RECRUITING

    Hot Springs, Arkansas, 71913, United States

  • Enveda Investigative Site

    RECRUITING

    Beverly Hills, California, 90212, United States

  • Enveda Investigative Site

    RECRUITING

    Fremont, California, 94538, United States

  • Enveda Investigative Site

    RECRUITING

    San Diego, California, 92121, United States

  • Enveda Investigative Site

    RECRUITING

    San Diego, California, 92123, United States

  • Enveda Investigative Site

    RECRUITING

    Santa Monica, California, 90403, United States

  • Enveda Investigative Site

    RECRUITING

    West Hills, California, 91307, United States

  • Enveda Investigative Site

    RECRUITING

    Fort Lauderdale, Florida, 33308, United States

  • Enveda Investigative Site

    RECRUITING

    Miami, Florida, 33175, United States

  • Enveda Investigative Site

    RECRUITING

    Miramar, Florida, 33027, United States

  • Enveda Investigative Site

    RECRUITING

    Atlanta, Georgia, 30327, United States

  • Enveda Investigative Site

    RECRUITING

    Chicago, Illinois, 60657, United States

  • Enveda Investigative Site

    RECRUITING

    Clarksville, Indiana, 47129, United States

  • Enveda Investigative Site

    RECRUITING

    New Albany, Indiana, 47150, United States

  • Enveda Investigative Site

    RECRUITING

    West Lafayette, Indiana, 47906, United States

  • Enveda Investigative Site

    RECRUITING

    Louisville, Kentucky, 40217, United States

  • Enveda Investigative Site

    RECRUITING

    Louisville, Kentucky, 40241, United States

  • Enveda Investigative Site

    RECRUITING

    Auburn Hills, Michigan, 48326, United States

  • Enveda Investigative Site

    RECRUITING

    Bay City, Michigan, 48706, United States

  • Enveda Investigative Site

    RECRUITING

    Clinton Township, Michigan, 48038, United States

  • Enveda Investigative Site

    RECRUITING

    Warren, Michigan, 48088, United States

  • Enveda Investigative Site

    RECRUITING

    Las Vegas, Nevada, 89145, United States

  • Enveda Investigative Site

    RECRUITING

    New York, New York, 10029, United States

  • Enveda Investigative Site

    RECRUITING

    Wilmington, North Carolina, 28405, United States

  • Enveda Investigative Site

    RECRUITING

    Canton, Ohio, 44718, United States

  • Enveda Investigative Site

    RECRUITING

    Mayfield Heights, Ohio, 44124, United States

  • Enveda Investigative Site

    RECRUITING

    Camp Hill, Pennsylvania, 17011, United States

  • Enveda Investigative Site

    RECRUITING

    Arlington, Texas, 76011, United States

  • Enveda Investigative Site

    RECRUITING

    Houston, Texas, 77004, United States

  • Enveda Investigative Site

    RECRUITING

    San Antonio, Texas, 78218, United States

  • Enveda Investigative Site

    RECRUITING

    Norfolk, Virginia, 23502, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.