Fruit salt fights indigestion in minutes – new study
NCT ID NCT07140341
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This completed Phase 3 trial tested whether ENO Lime, a fruit salt powder, can quickly ease symptoms of indigestion, acidity, and nausea. Forty adults with recent symptoms took a single dose, and their discomfort was measured before and 15 minutes after. The study aimed to see if this over-the-counter remedy provides fast symptom relief.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- ENO Lime (fruit salt powder containing Svarjiksara and lime flavor)
- What this could lead to
- If it works, this could confirm that ENO Lime provides fast relief from indigestion and acidity symptoms.
- What could go wrong
- This is a small, single-arm study with no placebo group, so results may not prove effectiveness. The 15-minute follow-up is very short, and long-term benefits are not assessed.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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40 people
The number who actually took part.
- Started
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Aug 2025
- Finished
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Sep 2025
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male and female participants with age 18-60 years (both inclusive). * Participants newly experiencing symptom/s of Ajeerna vyadhi for not more than 10 days. * Participants with at least one symptom of Ajeerna vyadhi (according to Charak Samhita and Madhav Nidan) that is acidity (heartburn), acid indigestion (epigastric pain), indigestion (abdominal discomfort), or associated nausea. * Participants with VAS score greater than or equal to (\>=) 40-mm and less than or equal to (\<=) 80-mm Ajeerna vyadhi (acidity, acid indigestion, indigestion, or associated nausea) at the Baseline visit. * Participants are able to read, understand, and provide written informed consent. * Participants who can understand and complete the VAS. Exclusion Criteria: * Participants with chronic and recurrent cases of Ajeerna vyadhi. * Participants with Updrava of Ajeerna vyadhi (Complications of indigestion). * Pregnant women (self-reported) and breastfeeding females or females intending to become pregnant during the study. * Participant had surgery in the last 14 days. * Participant has been exposed to barium meal 3 days before screening. * Participants already on any indigestion or acidity medication. * Participants taking any medicinal/over-the-counter (OTC)/ herbal medicine from the past 3 days. * Participants on medications that could interact with ENO Lime (example, antacids, proton pump inhibitors, or H2 blockers) as per the judgment of the Investigator/designee. * Participants with known hypersensitivity to any of the components of ENO Lime (Svarjiksara \[Shudh\], Nimbu Rasa \[Citrus limon, Fruit Juice Powder\]). * Participants with a history of gastrointestinal (GI) disorders such as peptic ulcers, gastritis, irritable bowel syndrome (IBS), or other serious GI diseases. * Participants with serious renal, hepatic, or cardiovascular diseases. * Participants on a sodium restricted diet example, those suffering from hypertension or congestive heart failure. * Participants who have participated in another clinical trial within the last 30 days. * Any participant who, in the opinion of the investigator, should not participate in the study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Lifepoint Hospital
Pune, Maharashtra, 411057, India
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Ojas Hospital
Pune, Maharashtra, 412101, India
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Shri Krishna Super Speciality Institute of Ayurveda
New Delhi, 110058, India
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