AI blood test could spot endometriosis without surgery
NCT ID NCT05245695
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new blood test called EndoCheck that uses artificial intelligence to detect endometriosis in women with chronic pelvic pain. Researchers aim to see if the test is accurate enough to replace or reduce the need for exploratory surgery. About 1,200 women aged 14 to 50 who are already scheduled for surgery will provide blood samples to check the test's sensitivity and specificity.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,200 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2022
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Women scheduled for a gynecologic surgery
- Ages
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14 to 50 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participant is willing and able to provide written informed consent. * Participant is a female aged 14 to 50 years old at time of consent. * Participant is scheduled to undergo laparotomy or laparoscopy for symptomology consistent with possible endometriosis Exclusion Criteria: * Participant is a female in a pre-menarchal state. * Participant is pregnant. * Participant has an active malignancy. * Participant is known to have tested positive for human immunodeficiency virus or hepatitis A, B, or C. * Participant has an active pelvic infection or other infections contraindicated for surgery. * Participant has participated (±3 months of study enrollment) in a clinical trial where an investigational drug/ device/ procedure was or is planned to be administered. * Participant has any general health or behavioral condition that, in the opinion of the investigator, should exclude the participant from participation. * Participant is under 14 years old or over 50 years old
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
10 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Show contact details
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Genom att skicka in godkänner du våra Användarvillkor
Locations
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Advanced Women's Care Center
RECRUITINGStockbridge, Georgia, 30281, United States
Contact Email: •••••@•••••
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Cindy Basinski, MD
RECRUITINGForest Hill, Indiana, 47630, United States
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Johns Hopkins School of Medicine
RECRUITINGBaltimore, Maryland, 21205, United States
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Midtown OBGYN North
RECRUITINGColumbus, Georgia, 31909, United States
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New Horizons Clinical Trials
RECRUITINGChandler, Arizona, 852224, United States
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Nezhat Surgery for Gynecology/Oncology
RECRUITINGValley Stream, New York, 11581, United States
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Reproductive Associates of Delaware (RAD)
RECRUITINGNewark, Delaware, 19713, United States
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Seven Hills Clinical Research
RECRUITINGCincinnati, Ohio, 45242, United States
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Velvet Clinical Research
RECRUITINGBurbank, California, 91506, United States
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Womens Health Services of Central Virginia
RECRUITINGLynchburg, Virginia, 24502, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can Pre-Surgery pelvic floor therapy stop endometriosis pain after the operation?
- Appendix: the hidden driver of endometriosis pain?
- Allergy pill put to the test against endometriosis pain
- Can ultrasound and tissue clues reveal which endometriosis lesions carry cancer risk?
- Can AI personalize exercise to ease pelvic pain?
- Can AI learn to spot endometriosis and fibroids on ultrasound?