10,000 patients join italian endometrial cancer data project
NCT ID NCT07558889
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to gather and analyze detailed medical information from 10,000 people diagnosed with endometrial cancer in Italy. Researchers will look at how the cancer's molecular and immune features affect how long patients stay free of the disease and how long they live overall. The goal is to build a powerful database to improve future treatment and understanding of this cancer.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 10,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2024
- Expected to finish
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Jan 2034
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
All patients undergoing staging and cytoreduction surgery for endometrial cancer will be included in the study. This database will make use of data collected retrospectively with prospectively continuously updated prognostic and clinical information. The following data will be collected: clinical characteristics (age, BMI, ASA, previous tumors), histopathological data (histotype, grade, FIGO stage, etc.) Furthermore, data will be collected relating to the adjuvant chemotherapy or radiotherapy treatment performed, survival outcome (DFS and OS), number of relapses and deaths, type of relapse, treatment at relapse, cause of death.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * diagnosis of endometrial cancer (stage I-IV, G1-3, and special histotypes) * age \> 18 years * American Society of Anesthesiologists classification (ASA score) 1-3 * patients undergoing staging, cytoreduction or diagnostic surgery with acquisition of histological examination on which IHC and/or NGS studies have been performed for the molecular profile of the carcinoma * Signed informed consent Exclusion Criteria: * patients with missing information * patients not treated in the participating centers for which only partial and fragmented information will be available * molecular profile not known and\\or not recoverable and retrospectively analysable
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Fondazione Policlinico Universitario Agostino Gemelli, IRCCS
RECRUITINGRoma, 00136, Italy
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