New hope for kids with rare calcium disease: encaleret trial launches
NCT ID NCT07080385
First seen Jan 23, 2026 · Last updated May 22, 2026 · Updated 12 times
Summary
This study tests a drug called encaleret in children (birth to 17 years) with autosomal dominant hypocalcemia type 1 (ADH1), a rare genetic condition causing low blood calcium and high urine calcium. The goal is to see if the drug can safely restore normal calcium levels in the blood and urine. About 28 children will take part in this open-label trial across multiple centers.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Children's National Medical Center
RECRUITINGWashington D.C., District of Columbia, 20010, United States
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Nemours Children's Health
RECRUITINGJacksonville, Florida, 32207, United States
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Royal London Hospital
RECRUITINGLondon, E1 1FR, United Kingdom
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Royal Manchester Children's Hospital
RECRUITINGManchester, M13 9WL, United Kingdom
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The Children's Hospital of Philadelphia
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Yale University
RECRUITINGNew Haven, Connecticut, 06511, United States
Conditions
Explore the condition pages connected to this study.