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Can electronic health records replace clinical trials? new study investigates

NCT ID NCT06675695

First seen Jan 30, 2026 · Last updated Jun 19, 2026 · Updated 25 times

Summary

This completed study looked at nearly 5,000 people with non-small cell lung cancer to see if information from electronic health records could produce the same results as a famous clinical trial called FLAURA. The goal was to understand when and how real-world data can be trusted for research. No new treatments were tested; instead, researchers compared outcomes for patients taking different lung cancer drugs as recorded in medical databases.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02120, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could show that real-world data can reliably mimic clinical trial results, potentially speeding up future research and reducing costs.

What could go wrong

This is an observational study using existing records, not a new treatment test. Results may not perfectly match the original trial due to data limitations or unmeasured factors.

Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.