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EMPOWER study aims to boost breast cancer screening in childhood cancer survivors

NCT ID NCT01579552

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Aug 06, 2026 · Updated 3 times

Summary

This study tests whether sending personalized print materials and a follow-up phone call can encourage women who had childhood cancer to get mammograms. Participants are 360 women aged 25-49 who received chest radiation as children and haven't had a mammogram in two years. The goal is to see if this simple approach increases screening rates and helps catch breast cancer early.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
behavioral intervention (mailed tailored print materials and telephone-delivered brief motivational interview)
What this could lead to
If successful, this could provide an effective way to increase breast cancer screening in high-risk childhood cancer survivors, potentially catching cancers earlier.
What could go wrong
This is a behavioral study, not a medical treatment, so it won't directly prevent or cure cancer. The results depend on participants' willingness to change behavior, and the study is relatively small (360 women).

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 360 people

The number the study aims to enrol. It can still change while the study runs.

Start date

Jul 2010

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 49 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participant in the CCSS cohort * Diagnosed with a childhood cancer prior to 21 years of age * Treated with \> 20 Gy of chest radiation (mantle, mediastinal, lung, or chest) * Age 25-49 years at time of enrollment into the study * Interval from chest radiation to the time of enrollment of \> 8 years * No mammogram or other breast imaging study in the 24 months prior to enrollment * English-speaking - The University of Colorado AMC Denver and MSKCC group are not capable of or equipped for conducting a brief motivational interviews by telephone in another language. Exclusion Criteria: * Diagnosed with breast cancer * Participated in the Project VISION feasibility study (exposed to part of the intervention)

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Center (All protocol activities)

    New York, New York, 10021, United States

  • St. Jude Children's Research Hospital

    Memphis, Tennessee, United States

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