EMPOWER study aims to boost breast cancer screening in childhood cancer survivors
NCT ID NCT01579552
First seen Jun 25, 2026 · Last updated Aug 06, 2026 · Updated 3 times
Summary
This study tests whether sending personalized print materials and a follow-up phone call can encourage women who had childhood cancer to get mammograms. Participants are 360 women aged 25-49 who received chest radiation as children and haven't had a mammogram in two years. The goal is to see if this simple approach increases screening rates and helps catch breast cancer early.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- behavioral intervention (mailed tailored print materials and telephone-delivered brief motivational interview)
- What this could lead to
- If successful, this could provide an effective way to increase breast cancer screening in high-risk childhood cancer survivors, potentially catching cancers earlier.
- What could go wrong
- This is a behavioral study, not a medical treatment, so it won't directly prevent or cure cancer. The results depend on participants' willingness to change behavior, and the study is relatively small (360 women).
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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About 360 people
The number the study aims to enrol. It can still change while the study runs.
- Start date
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Jul 2010
- Expected to finish
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Jul 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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25 to 49 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participant in the CCSS cohort * Diagnosed with a childhood cancer prior to 21 years of age * Treated with \> 20 Gy of chest radiation (mantle, mediastinal, lung, or chest) * Age 25-49 years at time of enrollment into the study * Interval from chest radiation to the time of enrollment of \> 8 years * No mammogram or other breast imaging study in the 24 months prior to enrollment * English-speaking - The University of Colorado AMC Denver and MSKCC group are not capable of or equipped for conducting a brief motivational interviews by telephone in another language. Exclusion Criteria: * Diagnosed with breast cancer * Participated in the Project VISION feasibility study (exposed to part of the intervention)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Memorial Sloan Kettering Cancer Center (All protocol activities)
New York, New York, 10021, United States
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St. Jude Children's Research Hospital
Memphis, Tennessee, United States
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