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New heart valve device under study for severe aortic stenosis

NCT ID NCT05804903

First seen Nov 17, 2025 · Last updated May 20, 2026 · Updated 20 times

Summary

This study tests a new device called the ALLEGRA Plus THV System for people with severe aortic stenosis (a narrowed heart valve) or a failed surgical valve. About 177 participants will receive the device to see if it is safe and works well. The main goals are to check survival and stroke rates after one year, and whether the device works correctly after 7 days.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Deutsches Herzzentrum Berlin

    Berlin, 13353, Germany

  • Herzzentrum - Luzerner Kantonsspital

    Lucerne, 6000, Switzerland

  • Hospital La Paz

    Madrid, 28046, Spain

  • III Katedra Kardiologii

    Katowice, 40-635, Poland

  • Klinika Kardiochirurgii

    Gdansk, 80-214, Poland

  • Oulu University Hospital

    Oulu, 90220, Finland

  • Reina Sofia Hospital

    Córdoba, 14004, Spain

Conditions

Explore the condition pages connected to this study.