New heart valve device under study for severe aortic stenosis patients

NCT ID NCT05804903

First seen Nov 17, 2025 · Last updated Jun 17, 2026 · Updated 25 times

Summary

This study is testing a new heart valve system (ALLEGRA Plus) in 177 people with severe aortic stenosis or a failed surgical valve. The goal is to see if the device is safe and works well. Participants will be followed for 12 months to check for death or stroke, and to see if the valve works properly after 7 days.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Deutsches Herzzentrum Berlin

    Berlin, 13353, Germany

  • Herzzentrum - Luzerner Kantonsspital

    Lucerne, 6000, Switzerland

  • Hospital La Paz

    Madrid, 28046, Spain

  • III Katedra Kardiologii

    Katowice, 40-635, Poland

  • Klinika Kardiochirurgii

    Gdansk, 80-214, Poland

  • Oulu University Hospital

    Oulu, 90220, Finland

  • Reina Sofia Hospital

    Córdoba, 14004, Spain

Conditions

The condition(s) this trial relates to.

aortic valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.