New heart valve system under study for severe aortic stenosis

NCT ID NCT05804903

First seen Nov 17, 2025 · Last updated May 06, 2026 · Updated 18 times

Summary

This study is testing a new device called the ALLEGRA Plus THV System for people with severe aortic stenosis or a failed surgical heart valve. The goal is to see if the device is safe and works well. About 177 participants will be enrolled, and researchers will track deaths, strokes, and device success over 12 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Deutsches Herzzentrum Berlin

    Berlin, 13353, Germany

  • Herzzentrum - Luzerner Kantonsspital

    Lucerne, 6000, Switzerland

  • Hospital La Paz

    Madrid, 28046, Spain

  • III Katedra Kardiologii

    Katowice, 40-635, Poland

  • Klinika Kardiochirurgii

    Gdansk, 80-214, Poland

  • Oulu University Hospital

    Oulu, 90220, Finland

  • Reina Sofia Hospital

    Córdoba, 14004, Spain

Conditions

Explore the condition pages connected to this study.