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Brain scans reveal how depression warps emotional thinking

NCT ID NCT05966532

First seen Jan 05, 2026 · Last updated Jun 18, 2026 · Updated 27 times

Summary

This study looks at how depression changes the way people process emotions and make decisions. Researchers will compare 120 adults with depression and 120 healthy adults, all aged 21 to 80, using brain scans and thinking tests. The goal is to understand the brain circuits involved, not to test a treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Texas Arlington

    Arlington, Texas, 76010, United States

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75390-9127, United States

Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.