Could a simple shot replace IV drips for severe bleeding disorder?
NCT ID NCT05500807
First seen Apr 09, 2026 · Last updated May 22, 2026 · Updated 11 times
Summary
This early-stage study tests whether emicizumab (Hemlibra), given as a shot under the skin, can safely prevent bleeding in people with severe von Willebrand disease or combined VWD/hemophilia A. Currently, severe bleeds require IV infusions of clotting factor. The trial enrolls 40 participants of any age (infants at least 3 kg) and will track bleeding events and side effects. If successful, this could reduce the need for frequent IV treatments.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Locations
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Bleeding and Clotting Disorders Institute (BCDI)
RECRUITINGPeoria, Illinois, 61614, United States
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Central Michigan University: Children's Hospital of Michigan
RECRUITINGMount Pleasant, Michigan, 48859, United States
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Children's Mercy Hospital
RECRUITINGKansas City, Missouri, 64108, United States
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Innovative Hematology, Inc. (IHI)
RECRUITINGIndianapolis, Indiana, 46260, United States
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Penn State College of Medicine
RECRUITINGHershey, Pennsylvania, 17033, United States
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St. Joseph's Children's Hospital - Center for Bleeding and Clotting Disorders
RECRUITINGTampa, Florida, 33607, United States
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Stanford University: Stanford Children's Health
RECRUITINGRedwood City, California, 94063, United States
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The Center for Comprehensive Care and Diagnosis of Inherited Blood Disorders (CIBD)
RECRUITINGOrange, California, 92868, United States
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UW Health Comprehensive Program for Bleeding Disorders
RECRUITINGMadison, Wisconsin, 53792, United States
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University of Miami - Miller School of Medicine
RECRUITINGCoral Gables, Florida, 33146, United States
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University of Michigan Medical School
RECRUITINGAnn Arbor, Michigan, 48109, United States
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Washington Center for Bleeding Disorders
RECRUITINGSeattle, Washington, 98101, United States
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Contact Email: •••••@•••••
Conditions
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