Could a simple shot replace IV treatments for severe bleeding disorder?

NCT ID NCT05500807

Recruiting now Disease control Sponsor: Bleeding and Clotting Disorders Institute Peoria, Illinois Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether emicizumab (Hemlibra), a medicine given as a shot under the skin, can safely prevent bleeding in people with severe von Willebrand disease (VWD) or combined VWD/hemophilia A. About 40 participants of any age (including infants) will receive the drug and be monitored for bleeds and side effects. If successful, it could offer a more convenient alternative to current IV treatments.

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Conditions

The condition(s) this trial relates to.

hemophilia A von Willebrand disease 3

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CONCOMITANT VWD AND HEMOPHILIA VON WILLEBRAND DISEASE, TYPE 3

Contacts and locations

Locations

Bleeding and Clotting Disorders Institute (BCDI)
RECRUITING

Peoria, Illinois, 61614, United States
Central Michigan University: Children's Hospital of Michigan
RECRUITING

Mount Pleasant, Michigan, 48859, United States
Children's Mercy Hospital
RECRUITING

Kansas City, Missouri, 64108, United States
Innovative Hematology, Inc. (IHI)
RECRUITING

Indianapolis, Indiana, 46260, United States
Penn State College of Medicine
RECRUITING

Hershey, Pennsylvania, 17033, United States
St. Joseph's Children's Hospital - Center for Bleeding and Clotting Disorders
RECRUITING

Tampa, Florida, 33607, United States
Stanford University: Stanford Children's Health
RECRUITING

Redwood City, California, 94063, United States
The Center for Comprehensive Care and Diagnosis of Inherited Blood Disorders (CIBD)
RECRUITING

Orange, California, 92868, United States
UW Health Comprehensive Program for Bleeding Disorders
RECRUITING

Madison, Wisconsin, 53792, United States
University of Miami - Miller School of Medicine
RECRUITING

Coral Gables, Florida, 33146, United States
University of Michigan Medical School
RECRUITING

Ann Arbor, Michigan, 48109, United States
Washington Center for Bleeding Disorders
RECRUITING

Seattle, Washington, 98101, United States

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