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Weekly injection trial aims to stop dangerous bleeds in rare blood disorder

NCT ID NCT05345197

Summary

This study is testing whether regular injections of emicizumab can prevent bleeding episodes in adults with acquired hemophilia A, a rare condition where the immune system attacks blood clotting factors. 51 participants will receive weekly injections alongside other immune-suppressing medications. Researchers will measure how many serious bleeds occur during 12 weeks of treatment.

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Contacts and locations

Locations

  • Bleeding and Clotting Disorders Institute

    Peoria, Illinois, 61614, United States

  • Emory University

    Atlanta, Georgia, 30308, United States

  • Georgetown University

    Washington D.C., District of Columbia, 20007, United States

  • Hemophilia Center of Western Pennsylvania

    Pittsburgh, Pennsylvania, 15213, United States

  • Indiana Hemophilia and Thrombosis Center, Inc.

    Indianapolis, Indiana, 46260, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Penn Blood Disorders Program, Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Tulane University

    New Orleans, Louisiana, 70112-2632, United States

  • UCSD Hemophilia and Thrombosis Treatment Center

    San Diego, California, 92121, United States

  • UVA Comprehensive Cancer Center

    Charlottesville, Virginia, 22908, United States

  • University of North Carolina

    Chapel Hill, North Carolina, 27514, United States

  • University of Oklahoma Health Sciences Center

    Oklahoma City, Oklahoma, 73104, United States

  • University of Vermont Medical Center

    Burlington, Vermont, 05401, United States

  • Versiti Inc.

    Milwaukee, Wisconsin, 53226, United States

  • Washington Center for Bleeding Disorders

    Seattle, Washington, 98101, United States

  • Washington University

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.