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New drug duo aims to deepen leukemia remission

NCT ID NCT07271667

First seen Jan 05, 2026 · Last updated Jun 12, 2026 · Updated 21 times

Summary

This study tests whether adding emavusertib to a standard targeted therapy (zanubrutinib) can improve outcomes for people with chronic lymphocytic leukemia (CLL) and other B-cell cancers. About 108 adults with CLL who have already received some treatment will take both drugs. The goal is to see if the combination can make cancer undetectable or shrink tumors, but ongoing medication is expected.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Azienda Ospedale Università Padova

    RECRUITING

    Padova, 35128, Italy

  • Azienda Ospedaliero Universitaria Maggiore Della Carità

    RECRUITING

    Novara, 28100, Italy

  • Hospital Universitario Fundación Jiménez Díaz - START MADRID

    RECRUITING

    Madrid, 28040, Spain

  • IRCCS Ospedale San Raffaele

    RECRUITING

    Milan, 20132, Italy

  • MD Anderson Cancer Center Madrid

    RECRUITING

    Madrid, 28033, Spain

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

  • Mt Sinai Comprehensive Cancer Center

    RECRUITING

    Miami Beach, Florida, 33140, United States

  • Ohio State University Comprehensive Cancer Center

    RECRUITING

    Columbus, Ohio, 43210, United States

  • Summit Medical Group

    RECRUITING

    Florham Park, New Jersey, 07932, United States

  • Texas Oncology - Sammons Cancer Center

    RECRUITING

    Dallas, Texas, 75246, United States

  • UPMC Hillman Cancer Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia B-cell neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.