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Weekly shot shows promise in major obesity trial

NCT ID NCT07321886

Disease control Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 21, 2026 · Updated 6 times

Summary

This study tests a new once-weekly injection called eloralintide to help adults with obesity or overweight lose weight. About 1980 people who do not have type 2 diabetes will take part for up to 75 weeks, with some continuing for 2 more years. The goal is to see if the drug safely reduces body weight and improves related health measures like waist size and blood pressure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 1,980 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Jul 2030

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Have Body Mass Index (BMI) at screening of the following: * 30 kilogram per square meter (kg/m2) OR * 27 kg/m2 with at least one of the following weight-related health conditions at screening: * high blood pressure * dyslipidemia * obstructive sleep apnea, or * heart disease * Have a stable body weight (\<5% body weight change) for 90 days prior to screening. * Have a history of at least one self-reported unsuccessful dietary effort to reduce body weight Exclusion Criteria: * Have a prior or planned surgical treatment for obesity (liposuction, cryolipolysis, or abdominoplasty allowed if performed \>1 year before screening) * Have a prior or planned endoscopic procedure and/or device-based therapy for obesity (prior device-based therapy acceptable if device removal was more than 6 months prior to screening) * Have type 1 diabetes or type 2 diabetes * Have had within 90 days prior to screening: * heart attack * stroke * coronary artery revascularization * unstable angina, or * hospitalization due to congestive heart failure * Have a history or diagnosis of New York Heart Association Functional Classification Class IV congestive heart failure * Have taken medications or alternative remedies intended for weight loss within 90 days of screening

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obesity Overweight

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    153 sites in 15 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • AHF Pensacola

    RECRUITING

    Pensacola, Florida, 32503, United States

  • AIM Research

    RECRUITING

    Merewether, 2291, Australia

  • ALPHA Recherche Clinique

    RECRUITING

    Québec, G3K 2P8, Canada

  • AMR Clinical

    RECRUITING

    Las Vegas, Nevada, 89119, United States

  • AMR Clinical

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • AMR Clinical

    RECRUITING

    Norfolk, Virginia, 23502, United States

  • ANIMA Research

    RECRUITING

    Diepenbeek, 3590, Belgium

  • Abbeywell Surgery

    RECRUITING

    Romsey, SO51 7QN, United Kingdom

  • Accellacare - Mt Pleasant

    RECRUITING

    Mt. Pleasant, South Carolina, 29464, United States

  • Adachi Kyosai Hospital

    RECRUITING

    Adachi-ku, 120-0022, Japan

  • Adult Medicine of Lake County, Inc.

    RECRUITING

    Mt. Dora, Florida, 32757, United States

  • Aggarwal and Associates Limited

    RECRUITING

    Brampton, L6T 0G1, Canada

  • Albuquerque Clinical Trials, Inc.

    RECRUITING

    Albuquerque, New Mexico, 87102, United States

  • All India Institute of Medical Sciences (AIIMS) - Nagpur

    RECRUITING

    Nagpur, 441108, India

  • Alpha Recherche Clinique

    RECRUITING

    Québec, G2J 0C4, Canada

  • Altnagelvin Area Hospital

    RECRUITING

    Londonderry, BT47 6SB, United Kingdom

  • AmBeNet GmbH

    RECRUITING

    Leipzig, 04107, Germany

  • American Research Centers of Florida

    RECRUITING

    Pembroke Pines, Florida, 33027, United States

  • Arcturus Healthcare , PLC, Troy Internal Medicine Research Division

    RECRUITING

    Troy, Michigan, 48098, United States

  • Ark Clinical Research - Fountain Valley

    RECRUITING

    Fountain Valley, California, 92708, United States

  • Ashton Medical Group - Chapel House

    RECRUITING

    Lancashire, OL6 6EW, United Kingdom

  • BAG Drs. Med. Quist PartG

    RECRUITING

    Mainz, 55128, Germany

  • Beijing Pinggu District Hospital

    RECRUITING

    Beijing, 101200, China

  • BioMed Research & Medical Center

    RECRUITING

    Miami, Florida, 33156, United States

  • Bluewater Clinical Research Group Inc.

    RECRUITING

    Sarnia, N7T 4X3, Canada

  • Bodyline Clinic - Openshaw

    RECRUITING

    Manchester, M11 1AA, United Kingdom

  • Boocs Clinic Fukuoka

    RECRUITING

    Fukuoka, 812-0025, Japan

  • Bradford on Avon Health Centre

    RECRUITING

    Bradford-on-Avon, BA15 1DQ, United Kingdom

  • CARDIAMET Investigaciones Médicas

    NOT_YET_RECRUITING

    Buenos Aires, C1014ACP, Argentina

  • CEDOES

    SUSPENDED

    Vitória, 29055450, Brazil

  • CEPIC - Centro Paulista de Investigação Clínica

    NOT_YET_RECRUITING

    São Paulo, 04266-010, Brazil

  • CONEXA Investigacion Clinica S.A.

    NOT_YET_RECRUITING

    Buenos Aires, 1012, Argentina

  • CPCLIN

    SUSPENDED

    São Paulo, 01228-200, Brazil

  • CRS Clinical Research Services Mannheim

    RECRUITING

    Mannheim, 68167, Germany

  • Cardiología Palermo

    NOT_YET_RECRUITING

    Buenos Aires, 1425, Argentina

  • Care Access - Lake Charles (Bayou Pines)

    RECRUITING

    Lake Charles, Louisiana, 70601, United States

  • Care Access - Quincy

    RECRUITING

    Quincy, Massachusetts, 02169, United States

  • Care Access - Sacramento

    RECRUITING

    Sacramento, California, 95831, United States

  • Care Hospitals Hyderabad- Banjara Hills

    RECRUITING

    Hyderabad, 500034, India

  • Centro Modelo de Cardiología

    NOT_YET_RECRUITING

    San Miguel de Tucumán, 4000, Argentina

  • Centro Médico Viamonte

    NOT_YET_RECRUITING

    Buenos Aires, C1120AAC, Argentina

  • Centro de Pesquisa Clínica de Marília - CPCLIM

    NOT_YET_RECRUITING

    Marília, 17504-072, Brazil

  • Centrum Terapii Wspolczesnej J. M. Jasnorzewska Spolka Komandytowo-Akcyjna

    RECRUITING

    Lodz, 90-338, Poland

  • Centrum Zdrowia Metabolicznego Pawel Bogdanski

    RECRUITING

    Poznan, 60-589, Poland

  • Chang Gung Memorial Hospital at Kaohsiung

    RECRUITING

    Kaohsiung Niao Sung Dist, 83301, Taiwan

  • Chase Medical Research, LLC

    RECRUITING

    Waterbury, Connecticut, 06708, United States

  • Chiayi Christian Hospital

    RECRUITING

    Chiayi City, 600, Taiwan

  • Chronos Pesquisa Clínica

    NOT_YET_RECRUITING

    Brasília, 72145-450, Brazil

  • Cicemo Srl

    NOT_YET_RECRUITING

    Buenos Aires, 1424, Argentina

  • Clinical Research Atlanta

    RECRUITING

    Stockbridge, Georgia, 30281, United States

  • Core Research Group

    RECRUITING

    Brisbane, 4064, Australia

  • Cotton O'Neil Clinical Research Center

    RECRUITING

    Topeka, Kansas, 66606, United States

  • Dawson Clinical Research Inc.

    RECRUITING

    Guelph, N1H 1B1, Canada

  • Desert Oasis Healthcare Medical Group

    RECRUITING

    Palm Springs, California, 92262, United States

  • Diabetes Zentrum Wilhelmsburg

    ACTIVE_NOT_RECRUITING

    Hamburg, 21109, Germany

  • Diabeteszentrum Hamburg West

    RECRUITING

    Hamburg, 22607, Germany

  • Diabetologische Schwerpunktpraxis Dr. Staudenmeyer & Dr. Schiwietz

    ACTIVE_NOT_RECRUITING

    Lingen, 49808, Germany

  • Diex Recherche Inc. Division Trois-Rivieres

    RECRUITING

    Trois-Rivières, G9A 4P3, Canada

  • East-West Medical Research Institute

    RECRUITING

    Honolulu, Hawaii, 96814, United States

  • Ekamed

    RECRUITING

    Lublin, 20-718, Poland

  • Emeritus Research

    RECRUITING

    Botany, 2019, Australia

  • Emeritus Research

    RECRUITING

    Camberwell, 3124, Australia

  • Endolife Speciality Hospitals

    RECRUITING

    Guntur, 522001, India

  • Fundación Respirar

    NOT_YET_RECRUITING

    Buenos Aires, C1426ABP, Argentina

  • Fusion Clinical Research

    RECRUITING

    Norwood, 5067, Australia

  • Gabinety TERPA

    RECRUITING

    Lublin, 20-333, Poland

  • Gachon University Gil Medical Center

    RECRUITING

    Namdong-gu, 21565, South Korea

  • Gauhati Medical College and Hospital

    RECRUITING

    Guwahati, 781032, India

  • Gezondheidshuis De Gloed

    RECRUITING

    Machelen, 9870, Belgium

  • Glenny Corp. S.A.

    NOT_YET_RECRUITING

    Buenos Aires, 1430, Argentina

  • Headlands Research - Scottsdale

    RECRUITING

    Scottsdale, Arizona, 85260, United States

  • Higashi Shinjuku Clinic

    RECRUITING

    Tokyo, 169-0072, Japan

  • IBPClin - Instituto Brasil de Pesquisa Clínica

    NOT_YET_RECRUITING

    Rio de Janeiro, 20241-180, Brazil

  • IMA Clinical Research San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

  • IMA Clinical Research St. Petersburg

    RECRUITING

    St. Petersburg, Florida, 33704, United States

  • IMA Clinical Research Warren

    RECRUITING

    Warren Township, New Jersey, 07059, United States

  • INECO Neurociencias Oroño

    NOT_YET_RECRUITING

    Rosario, 2000, Argentina

  • InnoDiab Forschung Gmbh

    ACTIVE_NOT_RECRUITING

    Essen, 45136, Germany

  • Instituto de Investigaciones Clínicas Córdoba

    NOT_YET_RECRUITING

    Córdoba, 5000, Argentina

  • Instituto de Pesquisa clinica de Campinas

    NOT_YET_RECRUITING

    Campinas, 13060-080, Brazil

  • Integral Pesquisa e Ensino

    SUSPENDED

    Votuporanga, 15500-269, Brazil

  • Iowa Diabetes and Endocrinology Research Center

    RECRUITING

    West Des Moines, Iowa, 50266, United States

  • JEM Research Institute

    RECRUITING

    Atlantis, Florida, 33462, United States

  • Jessa Ziekenhuis

    RECRUITING

    Hasselt, 3500, Belgium

  • Jiangsu Province Official Hospital

    RECRUITING

    Nanjing, 210008, China

  • Jiangxi Provincial People's Hospital

    RECRUITING

    Nanchang, 330038, China

  • Jinan Central Hospital

    RECRUITING

    Jinan, 250013, China

  • Kanno Naika

    RECRUITING

    Mitaka, 181-0013, Japan

  • Kaohsiung Medical University Chung-Ho Memorial Hospital

    RECRUITING

    Kaohsiung City, 807, Taiwan

  • Konyang University Hospital

    RECRUITING

    Seogu, 35365, South Korea

  • Kormont

    RECRUITING

    Kluisbergen, 9690, Belgium

  • Layton Medical Centre

    RECRUITING

    Blackpool, FY3 7EN, United Kingdom

  • Legeartis - Poradnie Specjalistyczne

    RECRUITING

    Bialystok, 15-404, Poland

  • Life Clinical Research

    RECRUITING

    Ipswich, 4305, Australia

  • Lifepoint Multispeciality Hospital

    RECRUITING

    Pune, 411057, India

  • Luhe Hospital

    RECRUITING

    Beijing, 1001199, China

  • MFA Clinical Research

    RECRUITING

    Tuscaloosa, Alabama, 35405, United States

  • Mandya Institute Of Medical Sciences

    RECRUITING

    Mandya, 571401, India

  • Med Trust Research

    RECRUITING

    Courtice, L1E 2J5, Canada

  • MedStar Good Samaritan Hospital

    RECRUITING

    Baltimore, Maryland, 21239, United States

  • MedStar Health Research Institute (MedStar Physician Based Research Network)

    RECRUITING

    Hyattsville, Maryland, 20782, United States

  • Medical Corporation Chiseikai Tokyo Center Clinic

    RECRUITING

    Chūōku, 103-0027, Japan

  • Medical Corporation Heishinkai OCROM Clinic

    RECRUITING

    Suita-shi, 565-0853, Japan

  • Medizentrum Essen Borbeck

    ACTIVE_NOT_RECRUITING

    Essen, 45355, Germany

  • Medyczne Centrum Diabetologiczno Endokrynologiczno Metaboliczne DIAB-ENDO-MET

    RECRUITING

    Krakow, 31-261, Poland

  • Momentum Sunshine

    RECRUITING

    Melbourne, 3021, Australia

  • Monroe Biomedical Research

    RECRUITING

    Monroe, North Carolina, 28112, United States

  • Mysore Medical College

    RECRUITING

    Mysore, 570001, India

  • Nanjing First Hospital

    RECRUITING

    Nanjing, 210000, China

  • National Taiwan University Hospital

    RECRUITING

    Taipei, 10002, Taiwan

  • Neighborhood Healthcare Institute of Health

    RECRUITING

    Escondido, California, 92025, United States

  • Nihonbashi Sakura Clinic

    RECRUITING

    Chūōku, 103-0025, Japan

  • Núcleo de Pesquisa Clínica do Rio Grande do Sul

    NOT_YET_RECRUITING

    Porto Alegre, 90430-001, Brazil

  • Paratus Clinical Research - Melbourne

    RECRUITING

    Melbourne, 3070, Australia

  • Paratus Clinical Research Central Coast

    RECRUITING

    Kanwal, 2259, Australia

  • Patient First Clinic Ginza-Shimbashi

    RECRUITING

    Minato, 105-0004, Japan

  • Peninsula Research Associates

    RECRUITING

    Rolling Hills Estates, California, 90274, United States

  • Prabhu Diabetes Multi-Speciality Centre

    RECRUITING

    Trichy, 620001, India

  • Pracownia Badań Klinicznych Salus

    RECRUITING

    Wroclaw, 53-034, Poland

  • Praxis Sauter & Sauter & Vorbach

    ACTIVE_NOT_RECRUITING

    Wangen, 88239, Germany

  • Preferred Primary Care Physicians

    RECRUITING

    Uniontown, Pennsylvania, 15401, United States

  • Private Practice - Dr.Miguel N. Hissa

    SUSPENDED

    Fortaleza, 60430-350, Brazil

  • Puerto Rico Health and Wellness Institute

    RECRUITING

    Dorado, 00646, Puerto Rico

  • Pusan National University Yangsan Hospital

    RECRUITING

    Yangsan, 50612, South Korea

  • RED-Institut GmbH

    ACTIVE_NOT_RECRUITING

    Oldenburg, 23758, Germany

  • Rame Group Practice

    RECRUITING

    Torpoint, PL11 2TB, United Kingdom

  • Rochester Clinical Research, LLC

    RECRUITING

    Rochester, New York, 14609, United States

  • Royal Lancaster Infirmary

    RECRUITING

    Lancaster, LA1 4RP, United Kingdom

  • Ruschel Medicina e Pesquisa Clínica

    NOT_YET_RECRUITING

    Rio de Janeiro, 22270-060, Brazil

  • Samodzielny Publiczny Szpital Kliniczny nr 1 SUM

    RECRUITING

    Zabrze, 41-800, Poland

  • Seoul National University Bundang Hospital

    RECRUITING

    Seongnam, 13620, South Korea

  • Seoul National University Hospital

    RECRUITING

    Seoul, 03080, South Korea

  • Shanghai Sixth People's Hospital

    RECRUITING

    Shanghai, China

  • Sichuan Provincial People's Hospital

    RECRUITING

    Chengdu, 610072, China

  • Southern California Clinical Research

    RECRUITING

    Santa Ana, California, 92701, United States

  • StudyPoint Duisburg

    ACTIVE_NOT_RECRUITING

    Duisburg, 47269, Germany

  • Supe Heart & Diabetes Hospital and Research Centre

    RECRUITING

    Nashik, 422002, India

  • Taipei Veterans General Hospital

    RECRUITING

    Taipei, 11217, Taiwan

  • Teak Research Consults

    RECRUITING

    Lawrenceville, Georgia, 30043, United States

  • Teak Research Consults - Dunwoody

    RECRUITING

    Dunwoody, Georgia, 30338, United States

  • The First Affiliated Hospital of Henan University of Science &Technology

    RECRUITING

    Luoyang Shi, 471003, China

  • The Second Affiliated Hospital of Nanjing Medical University

    RECRUITING

    Nanjing, 210011, China

  • The Second People's Hospital of Hefei

    RECRUITING

    Hefei, 230011, China

  • The University of Texas Health Science Center at Houston

    RECRUITING

    Bellaire, Texas, 77401, United States

  • The Wharton Medical Clinic Clinical Trials Inc

    RECRUITING

    Hamilton, L8L 5G8, Canada

  • Tokyo-Eki Center-building Clinic

    RECRUITING

    Chūōku, 103-0027, Japan

  • Topiwala National Medical College & B. Y. L. Nair Charitable Hospital

    RECRUITING

    Mumbai, 400008, India

  • Tribe Clinical Research, LLC

    RECRUITING

    Greenville, South Carolina, 29607, United States

  • USC Clinical Trials Sunshine Coast

    RECRUITING

    Sippy Downs, 4556, Australia

  • UT Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390-9302, United States

  • Universitaetsklinikum Carl Gustav Carus Dresden

    ACTIVE_NOT_RECRUITING

    Dresden, 01307, Germany

  • University Clinical Investigators, Inc.

    RECRUITING

    Tustin, California, 92780, United States

  • University of the Sunshine Coast (UniSC) Clinical Trials - Meadowbrook

    RECRUITING

    Meadowbrook, 4131, Australia

  • Velocity Clinical Research, Dallas

    RECRUITING

    Dallas, Texas, 75230, United States

  • Wansford Research Limited

    RECRUITING

    Peterborough, PE8 6PL, United Kingdom

  • Wellness clinical Research Vega Baja

    RECRUITING

    Vega Baja, 00693, Puerto Rico

  • West China Hospital Sichuan University

    RECRUITING

    Chengdu, 610041, China

  • Winterberry Research Inc.

    RECRUITING

    Stoney Creek, L8J 0B6, Canada

  • Zdrowie Osteo-Medic

    RECRUITING

    Bialystok, 15-351, Poland

  • Zentrum fur klinische Forschung - Köln

    ACTIVE_NOT_RECRUITING

    Cologne, 51069, Germany

  • Zhongda Hospital Southeast University

    RECRUITING

    Nanjing, 210009, China

  • Zhujiang Hospital

    RECRUITING

    Guangzhou, 510280, China

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