Can needle therapy heal your stomach? new trial aims to reverse chronic gastritis
NCT ID NCT07152860
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether electroacupuncture (a type of acupuncture with mild electrical pulses) can help reverse damage to the stomach lining in people with chronic atrophic gastritis. About 100 adults aged 18-75 will receive either electroacupuncture plus standard medication or medication alone for 24 weeks. The goal is to see if the combination can improve stomach tissue and reduce symptoms better than medication alone.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Meets the diagnostic criteria for chronic atrophic gastritis (CAG) (at the time of enrolment, participants must provide reports from endoscopic and pathological examinations conducted within the past year prior to the study start date, both of which indicate chronic atrophic gastritis) * Age between 18 and 75 years old, no gender restrictions; * Has not received acupuncture treatment within the past month; * Not participated in any other ongoing studies within the past 2 months. * Understand and agree to participate in this study and sign the informed consent form. Exclusion Criteria: * Autoimmune gastritis (type A chronic atrophic gastritis); * Participants with a positive C-13 urea breath test at baseline (Helicobacter pylori infection); * Patients diagnosed with high-grade intraepithelial neoplasia based on upper gastrointestinal endoscopy and gastric mucosal biopsy pathology; * Patients with confirmed or unresolved malignant tumours, particularly oesophageal cancer and gastric cancer; patients with other upper gastrointestinal lesions such as peptic ulcers or Barrett's oesophagus; * Patients with severe lesions in major organs (heart, liver, kidney, lung, etc.) or other autoimmune diseases (rheumatic diseases, Crohn's disease, autoimmune pancreatitis, etc.); Persons with cardiac pacemakers; * Pregnant and lactating women; * Patients with infectious diseases such as tuberculosis, hepatitis, or HIV/AIDS; * Individuals with a history of alcohol abuse, drug use, or illicit drug use; * Individuals who have used other prokinetic agents, mucosal protectants, acid-suppressing medications, or related traditional Chinese medicines within the past two weeks; * Individuals currently participating in or who have participated in other clinical trials within the past two months; individuals unable to tolerate acupuncture or with contraindications for acupuncture treatment; and individuals deemed unsuitable for participation in this clinical trial by the research team.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
3 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hangzhou First People's Hospital
Hangzhou, Zhejiang, 310053, China
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Hangzhou TCM Hospital of Zhejiang Chinese Medical University (Hangzhou Hospital of Traditional Chinese Medicine)
Hangzhou, Zhejiang, 310007, China
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The Third Affiliated Hospital of Zhejiang Chinese Medicinal University
Hangzhou, Zhejiang, 310053, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.