Can needles ease tummy troubles? new study tests electro-acupuncture for IBS-C
NCT ID NCT06219707
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed pilot study tested whether electro-acupuncture can improve symptoms of irritable bowel syndrome with constipation (IBS-C). Sixty IBS-C patients were randomly assigned to receive either real electro-acupuncture or a sham (fake) version. The study also collected blood, urine, and stool samples to explore how acupuncture might affect gut bacteria. The goal was to see if real acupuncture leads to better pain relief and more regular bowel movements compared to the sham treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- electro-acupuncture
- What this could lead to
- If it works, this could offer a non-drug option for managing IBS-C symptoms like pain and constipation.
- What could go wrong
- This is a small pilot study (60 participants) with no phase, so results are preliminary and may not apply to everyone. The sham control may also show some benefit, making it hard to prove real effect.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
60 people
The number who actually took part.
- Started
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Sep 2024
- Finished
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May 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
21 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Fulfilment of the Rome IV criteria for IBS-C; 2. Age of 21 to 65 years (inclusive); 3. Weekly average of worst daily abdominal pain score of ≥3 (0-10 scale) for at least 12 weeks before the first visit and during screening period; 4. \<3 complete spontaneous bowel movements (CSBMs) per week for at least 12 weeks before the first visit and during screening period; 5. Written informed consent. Exclusion Criteria: 1. Pregnancy or breast-feeding; 2. Medical history of inflammatory bowel diseases, carbohydrate malabsorption, hormonal disorder, known allergies to food additives, and/or any other serious diseases; 3. History of gastrointestinal tract segment removal or bariatric surgery for obesity; 4. Appendectomy or cholecystectomy within the past 2 months, or other abdominal surgeries within the past 6 months prior to trial enrollment; 5. Unstable medical conditions that could be associated with abdominal pain or discomfort and could potentially influence the assessments in this trial (e.g., chronic kidney disease, endometriosis, lactose intolerance); 6. Diagnosed with primary severe mental illness; 7. Patients who have received acupuncture treatment in last three months, or took concomitant medication with affect gastrointestinal motility or visceral sensation, such as antidiarrheal agent, antidepressant, narcotic analgesic, and anticholinergic; 8. Alcoholism or drug abuse in past 1 year; 9. Having needle phobia or allergy to acupuncture needle materials; 10. Antibiotics and probiotics/prebiotics usage in the previous month; 11. Participating in other clinical studies.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Nanyang Technological University, School of Biological Sciences
Singapore, Singapore, 637551, Singapore
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Other studies related to the condition(s) this trial covers.
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