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Zapping away nerve pain: 40 kHz currents tested in spinal injury patients

NCT ID NCT07359677

Symptom relief Sponsor: University of Castilla-La Mancha Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a mild electrical stimulation (40 kHz) applied through the skin can safely reduce nerve pain in people with spinal cord injury. Thirty adults with paraplegia and chronic nerve pain received either real or placebo stimulation alongside their usual treatment. The goal was to see if the device could lower pain scores over several weeks.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcutaneous electrical stimulation with 40 kHz alternating currents
What this could lead to
If it works, this could offer a non-drug option to ease nerve pain after spinal cord injury.
What could go wrong
This is a very small pilot study with only 30 people, so results may not apply widely. The treatment is still experimental and may not reduce pain better than placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Jan 2026

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * People with spinal cord injuries of any aetiology affecting the D1 spinal cord level or lower (paraplegia) * With injury grade A, B, C, or D according to the ASIA (American Spinal Injury Association) Impairment Scale (AIS) * Time since spinal cord injury ≥ 3 months * A score of ≥ 4 points on the Dolour Neuropathique 4 (DN4) scale * Neuropathic pain at the level of the injury (within the dermatome at that level and up to three dermatomes below) and/or below the level of the injury (more than three dermatomes below) * Duration of pain ≥ 1 month * Average pain perception score ≥ 30 mm on the visual analogue scale (VAS) in the week prior to eligibility, with a daily record of 5 days (Monday to Friday) in the morning. * Be able to understand instructions and assessment tools * Agree to participate in the study and sign the informed consent form Exclusion Criteria: * Cauda equina injuries * Brain injuries or other central nervous system injuries concomitant with spinal cord injury * A value of 100 mm in any of the daily records collected in the week prior to eligibility * Having any contraindications for the application of transcutaneous electrical stimulation: cardiac pacemaker or any other implanted electrical device, epilepsy, pregnancy, active malignant tumours in the area of application of the stimulation, and wounds or skin damage in the area of stimulation * History of psychiatric illness * Major depression * Spinal cord injury caused by autolysis * Changes in medication prescribed for the treatment of pain and spasticity during the study * Acute nociceptive pain in any area of the body during the study

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Conditions

The condition(s) this trial relates to.

neuralgia spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Neuropathic pain Spinal cord injuries (SCI)

Contacts and locations

Locations

  • Hospital Nacional de Parapléjicos

    Toledo, 45005, Spain

More trials for these conditions

Other studies related to the condition(s) this trial covers.