Could tiny needles zap knee pain away? new study investigates
NCT ID NCT07403448
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares adding electrical dry needling to standard physical therapy versus physical therapy alone for knee osteoarthritis. Forty-four adults aged 40-60 with moderate to severe knee pain will receive treatment for 6 weeks. Researchers will measure changes in pain, knee movement, daily function, and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- electrical dry needling
- What this could lead to
- If it works, this could offer a non-drug way to ease pain and improve knee function for people with osteoarthritis.
- What could go wrong
- This is a small, early-stage trial with only 44 participants. The results may not apply to everyone, and dry needling can cause temporary soreness or bruising.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 44 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * participants age group from 40-60 years * Both male and female genders * Knee osteoarthritis (OA) confirmed by radiographic evidence (Kellgren- Lawrence grade 3). * Numerical Pain Rating Scale (NPRS) ≥ 4/10. * Able to stand and bear weight on affected knee. * WOMAC score \> 25 moderate level of difficulty performing ADL * Participant with restricted range of motion * Pain while walking and ascending stairs * Patients volunteered to participate in the study and signed informed consent Exclusion Criteria: * Mild to severe knee osteoarthritis (Kellgren-Lawrence grade 2 or 4). * Recent knee surgery or injection (\<6 months). * Knee instability and ligamentous injury. * Pregnancy and breastfeeding. * Patient with needle phobia and with history of abnormal reaction to needles. * Diagnosed psychological disorders * Anticoagulant patient, tumors and hematomas. * All acute emergencies and acute systematic fevers. * Pacemakers and implantable cardioverter defibrillators
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Sheikh Khalifa Bin Zayed Hospital, Quetta
Quetta, Balochistan, 87900, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Thigh muscle clues may predict who gets knee pain relief
- Talking through pain: could counseling unlock better exercise for knee arthritis?
- Can education boost exercise compliance for chronic pain sufferers?
- Could a simple X-Ray measurement outperform BMI in knee surgery safety?