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Breakthrough liver fluke drug shows promise in largest safety trial yet

NCT ID NCT04230148

First seen Jan 04, 2026 · Last updated May 19, 2026 · Updated 16 times

Summary

This study tested the safety and effectiveness of EGATEN (triclabendazole) in 301 people aged 6 and older with fascioliasis, a parasitic liver infection. Participants received two doses of the drug 12 hours apart and were monitored for 90 days. The goal was to see if the treatment safely cures the infection without needing long-term medication.

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Contacts and locations

Locations

  • Novartis Investigative Site

    Medellín, Antioquia, 050010, Colombia

  • Novartis Investigative Site

    Alexandria, 21131, Egypt

  • Novartis Investigative Site

    Cairo, 11617, Egypt

  • Novartis Investigative Site

    San Martín de Porres, Lima region, 31, Peru

  • Novartis Investigative Site

    Cusco, 84, Peru

  • Novartis Investigative Site

    Istanbul, Fatih, 34093, Turkey (Türkiye)

  • Novartis Investigative Site

    Gaziantep, Sehitkamil, 27310, Turkey (Türkiye)

  • Novartis Investigative Site

    Sur, 21280, Turkey (Türkiye)

  • Novartis Investigative Site

    Van, 65080, Turkey (Türkiye)

  • Novartis Investigative Site

    Qui Nhon, Binh Dinh, 590000, Vietnam

Conditions

Explore the condition pages connected to this study.