Liver fluke drug proves safe in largest study yet

NCT ID NCT04230148

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested the safety and effectiveness of the drug EGATEN (triclabendazole) in 301 people aged 6 and older with fascioliasis, a parasitic liver infection. Participants received two doses of EGATEN 12 hours apart and were followed for 90 days. The goal was to see if the drug is safe and can cure the infection by clearing symptoms and lab abnormalities.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Novartis Investigative Site

    Medellín, Antioquia, 050010, Colombia

  • Novartis Investigative Site

    Alexandria, 21131, Egypt

  • Novartis Investigative Site

    Cairo, 11617, Egypt

  • Novartis Investigative Site

    San Martín de Porres, Lima region, 31, Peru

  • Novartis Investigative Site

    Cusco, 84, Peru

  • Novartis Investigative Site

    Istanbul, Fatih, 34093, Turkey (Türkiye)

  • Novartis Investigative Site

    Gaziantep, Sehitkamil, 27310, Turkey (Türkiye)

  • Novartis Investigative Site

    Sur, 21280, Turkey (Türkiye)

  • Novartis Investigative Site

    Van, 65080, Turkey (Türkiye)

  • Novartis Investigative Site

    Qui Nhon, Binh Dinh, 590000, Vietnam

More trials for these conditions

Other studies related to the condition(s) this trial covers.