Heart surgery study tests simple Blood-Saving trick
NCT ID NCT07420582
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is for adults having planned heart bypass surgery. It tests a technique where leftover blood from the heart-lung machine is returned to the patient right after surgery. The goal is to see if this reduces the need for blood transfusions in the first 24 hours. Researchers will compare patients who get this treatment with those who do not, without changing any other care.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 130 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population includes adult patients (18-80 years) scheduled for elective, primary isolated coronary artery bypass grafting (CABG) using cardiopulmonary bypass at Kocaeli City Hospital.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 to 80 years * Patients undergoing elective, isolated coronary artery bypass grafting surgery using cardiopulmonary bypass (on-pump). Exclusion Criteria: * Emergency or Redo cardiac surgery * Concomitant cardiac procedures (e.g., valve repair/replacement or aortic surgery). * Planned or intraoperative conversion to off-pump coronary artery bypass grafting * Preoperative hematocrit \<30% or known inherited/acquired bleeding disorders. * Preoperative left ventricular ejection fraction \<30%. * Thrombocytopenia (e.g., platelet count \<100×10³/µL) or abnormal coagulation tests. * Use of antiplatelet agents other than aspirin without appropriate discontinuation according to current guideline-recommended preoperative intervals. * Use of anticoagulant therapy without appropriate preoperative discontinuation according to current guideline recommendations. * Use of non-steroidal anti-inflammatory drugs (NSAIDs) without appropriate discontinuation prior to surgery. * Severe renal dysfunction (eGFR \<30 mL/min/1.73 m² or dialysis) and/or severe hepatic dysfunction (Child-Pugh B-C or coagulopathy). * Active infection or systemic inflammatory/autoimmune disease. * Active malignancy requiring ongoing treatment * Refusal or inability to provide written informed consent.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Kocaeli City Hospital
RECRUITINGKocaeli, Izmit, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Heart bypass surgeons test which vein layout keeps grafts open
- A soft patch that watches your heart beat in real time
- Zapping the ear: a new way to stop Post-Surgery heart rhythm problems?
- Squeeze a ball, lower your blood pressure? heart trial puts handgrip exercise to the test
- New heart scan aims to spot hidden plaque before it strikes
- Can a kidney ultrasound scan warn of kidney damage after heart bypass surgery?