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Scientists test short bursts of low oxygen on healthy volunteers

NCT ID NCT04691518

Knowledge-focused Sponsor: Shirley Ryan AbilityLab Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how a single session of short, mild low-oxygen breathing (acute intermittent hypoxia) changes hand strength in healthy adults. Researchers want to understand how this technique affects the brain and spinal cord. The results will help design future therapies for people with nerve injuries. The study involves 32 healthy volunteers aged 18–70.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 32 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2016

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * No history of neurologic injury or progressive neuromuscular disorder * Individuals ages 18-70 years old * Must be medically stable with no history of cardiovascular instability, congestive heart failure or stroke * Not currently (\>2 weeks) on any medications related to spasticity * No history of Sleep apnea * Not a current smoker * Able to comply with protocol/study requirements Exclusion Criteria: * Recent change in the use of narcotic, anti-inflammatory or pain medication * unstable medical conditions or any other clinical observation that may affect the candidate's performance, health, safety or the ability to participate in the study determined by the treating therapist or coordinating staff * Active participation in another movement research study or therapy program * Anti-spasticity drug injection less than 3 months prior to beginning treatment * Musculoskeletal pain that interferes with participation in study * Women who are currently, may be, or planning on becoming pregnant * for fMRI participation, participants will be excluded if they have: * Metal fragments in eyes or face * Implantation of any electronic devices such as (but not limited to) cardiac pacemakers, cardiac defibrillators, cochlea implants, or nerve stimulators * Vascular surgery * Claustrophobia * Body piercing or tattoos

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Shirley Ryan AbilityLab

    Chicago, Illinois, 60611, United States

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