Can a scalp cap read the brain as well as implanted wires?
NCT ID NCT03629743
First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time
Summary
This study explores how well non-invasive scalp electrodes (EEG) match up with brain signals recorded directly from implanted electrodes (ECOG) in people undergoing anesthesia. Researchers will track brain activity and consciousness levels before, during, and after anesthesia in about 20 adults with epilepsy who already need implanted electrodes for medical reasons. The goal is to better understand how surface EEG reflects deep brain activity, which could improve anesthesia monitoring in the future.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Surface EEG and implanted ECOG recordings
- What this could lead to
- If successful, this could improve how doctors monitor consciousness during anesthesia, potentially leading to safer anesthesia care.
- What could go wrong
- This is a small, early-stage observational study with only 20 participants, so findings may not apply broadly. It does not test a treatment, so it won't directly change patient care.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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20 people
The number who actually took part.
- Started
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Nov 2019
- Finished
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Aug 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Stanford Health Care and Clinics
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male or Female subjects 18 years of age or older. * English or Spanish Speaking * Subjects who have been previously diagnosed with intractable epilepsy and require implantation of invasive electrophysiological recordings as part of their routine clinical presurgical workup. Exclusion Criteria: * Patients with skin abnormalities at the planned application sites that would interfere with sensor or electrode applications. * Patients with pre-existing conditions and/or co-morbidities that would prohibit them from participating in the study due to unacceptable risks to their health and well-being, as determined by the Principal Investigator (PI). * Patients who the PI deems ineligible at the PI's discretion * Pregnant patients
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Stanford University
Stanford, California, 94305, United States
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