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Emergency rooms could be key to ending HIV: new study tests simple PrEP strategies

NCT ID NCT05588193

Prevention Sponsor: Albert Einstein College of Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two low-burden strategies to increase HIV PrEP use among emergency department patients seeking care for sexual health issues. One strategy involves follow-up outreach after the visit, while the other offers a tele-sexual health visit during the ER stay. The goal is to see which approach helps more at-risk patients start PrEP, a daily pill that prevents HIV.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
behavioral interventions (post-visit outreach and tele-sexual health visit)
What this could lead to
If successful, this could provide simple, effective ways to start HIV prevention medication for people who visit emergency rooms for sexual health concerns, helping reduce new HIV infections.
What could go wrong
This is an implementation study, not a drug trial, so it tests how to deliver existing prevention tools rather than a new cure. Results may vary across different communities and emergency departments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

1,560 people

The number who actually took part.

Started

Oct 2024

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria for Two-Arm Trial: * Patient is \>=18 years at time of index ED visit * Patient presents to one of the Montefiore ED study sites * The ED provider applies at least one of the pre-selected International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM) codes to the encounter and manual review by SHN confirms the visit is related to sexual health Exclusion Criteria for Two-Arm Trial: * Patient is admitted to the hospital from the ED * Known HIV-positive status

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Conditions

The condition(s) this trial relates to.

HIV infectious disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV

Contacts and locations

Locations

  • City University of New York - Hunter College

    New York, New York, 10031, United States

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

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