Memory loss study cancelled before it began
NCT ID NCT06733558
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study was designed to understand why electroconvulsive therapy (ECT) sometimes causes temporary memory problems. Researchers planned to measure brain waves in people with severe depression or bipolar disorder receiving ECT. The study was withdrawn before any participants were enrolled, so no results are available.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Early phase 1
The earliest testing in people: a first look at safety, in a very small group.
- Started
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Jan 2025
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: * diagnosis of major depressive disorder (MDD; with or without psychotic features) or bipolar 2 most recent episode depressed; * clinical indications for ECT with right unilateral electrode placement including treatment resistance or a need for a rapid and definitive response, * age range adults 18-85 years, and * English-speaking (many of the neuropsychological tests are only available in English). Antidepressant medications will be continued as clinically indicated. To maintain feasibility and retention, as needed medications will be permitted for anxiety and insomnia. Exclusion criteria: * Defined neurological or neurodegenerative disorder (e.g., traumatic brain injury, epilepsy, Alzheimer's disease); * other psychiatric conditions (e.g., schizophrenia, bipolar I disorder); * current drug or alcohol use disorder (except for nicotine); * prisoners; and * pregnancy (pre- menopausal participants will receive pregnancy test, which is clinically indicated for ECT and not part of study protocol).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Domenici Hall
Albuquerque, New Mexico, 87106, United States
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