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Targeted eccentric exercise may rebuild shoulder function — a trial puts it to the test

NCT ID NCT07727941

Symptom relief Sponsor: Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This trial investigates whether eccentric isokinetic exercise — a type of controlled, lengthening muscle contraction performed on a special machine — can reduce pain and improve shoulder function in people with rotator cuff tendinopathy. Fifty adults aged 20 to 50 with confirmed tendinopathy will either do this machine-based exercise plus a standard home program, or the home program alone. Researchers will measure changes in pain, shoulder function, and muscle structure using ultrasound.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
eccentric isokinetic exercise on a Humac Norm II device
What this could lead to
If effective, this could offer a targeted exercise approach to ease shoulder pain and improve function without surgery.
What could go wrong
This is a small, early-stage trial with only 50 participants, so results may not apply broadly. The exercise program requires special equipment, limiting accessibility.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

50 people

The number who actually took part.

Started

Jul 2025

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients presenting to the Prof. Dr. Cemil Taşcıoğlu City Hospital Physical Therapy Outpatient Clinic with complaints of shoulder pain.

Ages

20 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria:Being between the ages of 20 and 50 * Having a diagnosis of rotator cuff tendinopathy based on medical history, physical examination, and MRI findings * Having full shoulder joint range of motion * Absence of upper extremity deformity that would interfere with ultrasonographic measurement * Having provided written informed consent Exclusion Criteria:Glenohumeral instability * Adhesive capsulitis (stages 2-3) * Radiographic evidence of calcific tendinitis or significant bursitis •Cervical radiculopathy Upper extremity or spinal deformities * History of surgery involving the shoulder, cervical spine, or back * Neurological or systemic disease (rheumatological, metabolic, etc.) * Physical therapy for the shoulder, neck, or back region within the last 6 months * Corticosteroid injection into the affected shoulder within the last 6 months * Exposure to intensive repetitive shoulder movements in sports or occupational activities * Use of medications that could affect exercise performance or metabolic response

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Conditions

The condition(s) this trial relates to.

disease of the tendon rotator cuff syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Rehabilitation exercise Rotator cuff tendinopathy

Contacts and locations

Locations

  • Prof. Dr. Cemil Taşcıoğlu City Hospital

    Istanbul, Turkey (Türkiye)

  • Prof. Dr. Cemil Taşcıoğlu City Hospital

    Istanbul, şişli, 34384, Turkey (Türkiye)

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