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Severe trauma and clotting: new study reveals hidden risks

NCT ID NCT07186712

Knowledge-focused Sponsor: Medical University of Graz Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 263 severely injured trauma patients to find out how often they develop early blood clotting problems (called trauma-induced coagulopathy) and excessive clot breakdown (hyperfibrinolysis) within the first hour of arriving at the emergency room. Researchers used a special test called thrombelastogram (TEG) along with standard lab tests. The goal was to better understand who is at risk, which could help doctors treat these life-threatening conditions faster.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

263 people

The number who actually took part.

Started

May 2025

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

patients with severe trauma (ISS\>16)

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age \< 18 years * Sever trauma (ISS\>16) * Coagulation parameters (PT, aPTT, INR, fibrinogen, TEG) available within the first hour of admission Exclusion Criteria: * Patients with known pre-existing coagulopathies * Patients on anticoagulant therapy prior to trauma * Incomplete or missing coagulation data

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Conditions

The condition(s) this trial relates to.

injury tic disorder Tics vascular hemostatic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Early trauma induced coagulopathy Tic

Contacts and locations

Locations

  • Medical University of Graz

    Graz, 8043, Austria