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Ankle fracture study: early joint wash may limit damage

NCT ID NCT05465382

First seen Nov 20, 2025 · Last updated May 21, 2026 · Updated 29 times

Summary

This study looked at whether washing out the ankle joint with saline within 48 hours of a fracture could lower harmful inflammation and cartilage breakdown. Researchers measured changes in inflammatory markers and cartilage products in the joint fluid of 41 adults. The goal was to understand if early intervention could protect the joint before surgery.

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Contacts and locations

Locations

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

Conditions

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