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Heart ultrasound may predict defibrillator need after heart attack

NCT ID NCT05285631

Knowledge-focused Sponsor: Aswan University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a special heart ultrasound (speckle tracking echocardiography) can predict which patients need an implantable defibrillator (ICD) after a large heart attack. Researchers followed 200 patients for 90 days to see whose heart function stayed low enough to qualify for an ICD. The goal is to identify high-risk patients earlier so they can get life-saving devices sooner.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors identify high-risk patients earlier after a heart attack, potentially preventing sudden cardiac death.
What could go wrong
This is a completed observational study, not a treatment trial. The prediction models need further validation before they can be used in routine care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

200 people

The number who actually took part.

Started

May 2022

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients presenting by acute anterior myocardial infarction, with baseline echocardiographic assessment demonstrating LVEF \< 40%.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 80 years. Both genders are eligible. * Patients with diagnosis of an acute anterior STEMI and revascularized with successful primary percutaneous coronary intervention (PCI) within 24 hours. * LVEF \< 40 % assessed by Bi-plane Simpsons rule within 48 hour post PCI. Exclusion Criteria: * ● Refusal to participate in the study. * Patients with existing ICD or pacemakers. * Qualifying ICD for secondary prevention. * Known to have LVEF ≤ 40% prior to the index MI. * Previous PCI to Left anterior Descending artery (LAD). * Previous or being scheduled for CABG within ≤ 3 months. * Known to have limited life expectancy (less than 1-year) prior to the index MI. * Pregnant or lactating women.

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Conditions

The condition(s) this trial relates to.

anterolateral myocardial infarction ST-elevation myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anterior mi

Contacts and locations

Locations

  • Magdi Yacoub Foundation

    Aswān, Egypt

More trials for these conditions

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