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Hormone clues may explain why PWS babies go from feeding trouble to obesity

NCT ID NCT02529085

First seen Apr 11, 2026 · Last updated Apr 29, 2026 · Updated 3 times

Summary

This study followed 215 infants with Prader-Willi syndrome (PWS) over their first four years of life. Researchers measured hormones that control hunger and appetite to understand why children with PWS switch from poor feeding in infancy to extreme hunger and obesity later. No treatments were tested; the goal was to gather information and create a blood sample bank for future research.

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Contacts and locations

Locations

  • Department of Endocrinology / University Children's Hospital

    Essen, Germany

  • Department of Pediatrics / Division of Endocrinology

    Toulouse, Haute-Garonne, 31000, France

  • Department of Pediatrics / Division of Endocrinology / Erasmus University Medical Center / Sophia Children's Hospital Rotterdam

    Rotterdam, 3015 GJ, Netherlands

  • Karolinska University Hospital

    Stockholm, Sweden

  • Metabolic & Molecular Imaging Group / MRC Clinical Sciences Centre / Imperial College London / Hammersmith Hospital

    London, W12 0NN, United Kingdom

  • Unité d'Endocrinologie Pédiatrique / Université Catholique de Louvain

    Brussels, 1200, Belgium

Conditions

Explore the condition pages connected to this study.