New study aims to catch hidden brain diseases during driver Check-Ups
NCT ID NCT07360886
First seen Jun 27, 2026 · Last updated Sep 09, 2026 · Updated 2 times
Summary
This study is looking for simple ways to detect early signs of multiple sclerosis and Parkinson's disease in people who drive. Researchers will test 200 drivers with these conditions using computer-based attention and reaction tests. The goal is to find quick, easy tests that could be used during routine driver medical exams to catch these diseases earlier and make roads safer.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to simple, routine tests that catch early signs of multiple sclerosis or Parkinson's disease during driver medical check-ups, improving road safety and early diagnosis.
- What could go wrong
- This is an early observational study with only 200 participants, so results may not apply to all drivers. The tests being studied are not yet proven to reliably detect these diseases.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 200 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients from the dispensary care of the neurological department of the University hospital Olomouc with the full access to the paraclinical data and demographic features.
- Ages
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18 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Person after signing informed consent. * After meeting the valid diagnostic criteria for the given neurological diagnosis. * Possession of a valid driver's license and proof of active driving. * Age limit 18 - 85 years. Exclusion Criteria: * Proven diagnosis of dementia based on a current psychological examination (MMSE 24 points or less). * Diagnosis of a disease or condition that, according to Czech Law. No. 277/2004 Coll., on medical fitness to drive motor vehicles, as amended (especially Law No. 204/2025 Coll.), prevents or significantly limits the ability to drive a motor vehicle safely (e.g. dementia, epilepsy, severe disorders of consciousness). * Age less than 18 years. * Age more than 85 years. * In the second cohort (patients with Multiple Sclerosis), proven and treated relapse in the last 6 weeks before inclusion in the study. * In the MS cohort, current EDSS \> 6.5 points. * For the PD cohort, the current Hoehn and Yahr scale score is greater than or equal to 4. * For both cohorts, evidence of parainfectious deterioration as demonstrated by laboratory testing.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University hospital Olomouc
RECRUITINGOlomouc, Olomouc Region, 779 00, Czechia
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