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Can early chemo beat the clock against colon cancer?

NCT ID NCT01460589

First seen Feb 18, 2026 · Last updated Jun 22, 2026 · Updated 13 times

Summary

This study looks at whether starting chemotherapy 10 to 14 days after surgery for stage III colon cancer is better than waiting the usual 2 weeks or more. About 300 patients are taking part to see if earlier treatment improves survival and lowers the chance of cancer coming back. The trial also checks for side effects and quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Jun Seok Park

    Daegu, South Korea

  • Kyungpook National University Medical center

    Daegu, 41404, South Korea

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

FOLFOX chemotherapy (oxaliplatin, leucovorin, 5-FU)

What this could lead to

If early chemotherapy works better, it could become a new standard to reduce cancer recurrence and improve survival for stage III colon cancer patients.

What could go wrong

This is a moderate-sized phase 3 trial, but results may not apply to all patients. Early chemo could increase side effects or complications without clear benefit.

Conditions

The condition(s) this trial relates to.

colon carcinoma colonic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.