Sound waves may catch kidney damage sooner after surgery
NCT ID NCT04144894
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study is testing a new ultrasound technique called Shear Wave Elastography to see if it can detect acute kidney injury early after vascular surgery. Researchers will compare results from 50 healthy volunteers and surgery patients. The goal is to find a quick, non-invasive way to diagnose kidney problems sooner.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Shear Wave Elastography (advanced ultrasound)
- What this could lead to
- If successful, this could provide a non-invasive way to detect kidney injury earlier after surgery, potentially improving outcomes.
- What could go wrong
- This is a small, early exploratory study with only 50 participants, so results may not apply broadly. The technique may not prove accurate enough for routine use.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2020
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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19 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * No history of diabetes or hypertension * Estimated Glomerular Filtration Rate \> 60 ml/min/m\^2 * Structurally normal kidney on renal ultrasound * BMI \< 27 kg/m\^2 Exclusion Criteria: * Prisoners directly admitted from a correctional facility * Children \< 19 years or under 50 kg body weight if age is unknown * Patients with end stage renal disease or preexisting glomerular filtration rate less than or equal to 30 mL/min/1.73 m\^2 or need for dialysis * Patients with end stage heart disease on the cardiac transplant list * Patients undergoing procedures without vascular surgery * All transplant patients * Patients on ventricular assist devices * Patients undergoing emergency procedures * Patients with body mass index \> 27kg/m\^2 * Any condition that would impede visualization of the kidneys by ultrasound
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35249, United States
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- Can watching kidney oxygen during liver surgery keep kidneys safe?