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Ear freeze for back pain? scientists scan brain to find out

NCT ID NCT06825390

First seen Feb 18, 2026 · Last updated Jun 23, 2026 · Updated 17 times

Summary

This study is testing whether a quick cold spray on specific ear points can change how the brain processes chronic low back pain. Sixty adults with back pain for at least 6 months will get either real or fake (sham) ear stimulation. Researchers will use brain scans (fNIRS and MRI) to compare brain activity before and after treatment. The goal is to understand the mechanism, not to prove pain relief.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cryo-auriculotherapy (cold gas applied to ear points)

What this could lead to

If it works, this could help explain how ear stimulation relieves pain, potentially leading to better non-drug treatments for chronic back pain.

What could go wrong

This is a small, early-stage study focused on brain changes, not pain relief. It may not show a clear benefit, and results may not apply to everyone with back pain.

Conditions

The condition(s) this trial relates to.

Back Pain Low Back Pain lumbar disk degenerative disorder post laminectomy syndrome somatoform disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.