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New antibody EA5 targets rare blood disorder PNH in early trial

NCT ID NCT07256301

First seen Jan 11, 2026 · Last updated May 20, 2026 · Updated 21 times

Summary

This early-stage trial tests a new drug called EA5 in 24 adults with paroxysmal nocturnal hemoglobinuria (PNH), a rare blood disease where red blood cells are destroyed. The main goal is to check if EA5 is safe and how it moves through the body. EA5 is an antibody designed to block part of the immune system that attacks blood cells in PNH, aiming to control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Affiliated Hospital, Zhejiang University School of Medicine, Chengzhan Campus

    RECRUITING

    Hangzhou, Zhejiang, 310009, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Institute of Hematology & Blood Diseases Hospital (Chinese Academy of Medical Sciences)

    RECRUITING

    Tianjin, Tianjin Municipality, 300020, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.