New antibody EA5 targets rare blood disorder PNH in early trial

NCT ID NCT07256301

First seen Jan 11, 2026 · Last updated May 15, 2026 · Updated 19 times

Summary

This study tests a new drug called EA5 in 24 adults with paroxysmal nocturnal hemoglobinuria (PNH), a rare blood disease that destroys red blood cells. The main goal is to check if multiple doses of EA5 are safe and how the body processes it. This is an early-stage trial to gather information for future studies.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Affiliated Hospital, Zhejiang University School of Medicine, Chengzhan Campus

    RECRUITING

    Hangzhou, Zhejiang, 310009, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Institute of Hematology & Blood Diseases Hospital (Chinese Academy of Medical Sciences)

    RECRUITING

    Tianjin, Tianjin Municipality, 300020, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.