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New combo aims to shrink Hard-to-Treat tumors

NCT ID NCT04078295

First seen Jan 04, 2026 · Last updated May 23, 2026 · Updated 30 times

Summary

This study tests a new drug (E7389 liposomal) combined with an immunotherapy (nivolumab) in people with advanced solid tumors that have not responded to standard treatments. The goal is to find the safest dose and see if the combination can shrink tumors. About 125 adults with certain cancers like gastric, esophageal, or small cell lung cancer are taking part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Eisai Trail Site #16

    Sunto-g, Shizuo, Japan

  • Eisai Trial Site #1

    Chuo Ku, Tokyo, Japan

  • Eisai Trial Site #10

    Koto-Ku, Tokyo, Japan

  • Eisai Trial Site #11

    Akashi, Hyōgo, Japan

  • Eisai Trial Site #12

    Kōtoku, Japan

  • Eisai Trial Site #13

    Nagoya, Aichi-ken, Japan

  • Eisai Trial Site #14

    Matsuya, Ehime, Japan

  • Eisai Trial Site #15

    Yokohama, Kanaga, Japan

  • Eisai Trial Site #17

    Suita, Osaka, Japan

  • Eisai Trial Site #18

    Kashiwa, Chiba, Japan

  • Eisai Trial Site #19

    Kitaadachi-gun, Saitama, Japan

  • Eisai Trial Site #2

    Kashiwa, Chiba, Japan

  • Eisai Trial Site #3

    Sendai, Miyagi, Japan

  • Eisai Trial Site #4

    Kurume, Fukuoka, Japan

  • Eisai Trial Site #5

    Osakasa, Osaka, Japan

  • Eisai Trial Site #6

    Chuo Ku, Osaka, Japan

  • Eisai Trial Site #7

    Sakai C, Osaka, Japan

  • Eisai Trial Site #8

    Chuo Ku, Osaka, Japan

  • Eisai Trial Site #9

    Wakayama, Wakaya, Japan

Conditions

Explore the condition pages connected to this study.