New combo therapy shows promise for Hard-to-Treat cancers

NCT ID NCT04078295

Ongoing Disease control Sponsor: Eisai Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug combination (E7389 liposomal formulation plus nivolumab) in 125 people with advanced solid tumors that have not responded to standard treatments. The goal is to find the safest dose and see if the combination can shrink tumors. The study is for people with certain cancers like gastric, esophageal, or small cell lung cancer.

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Conditions

The condition(s) this trial relates to.

esophageal cancer gastric cancer neoplasm small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SOLID NEOPLASMS

Contacts and locations

Locations

Eisai Trail Site #16

Sunto-g, Shizuo, Japan
Eisai Trial Site #1

Chuo Ku, Tokyo, Japan
Eisai Trial Site #10

Koto-Ku, Tokyo, Japan
Eisai Trial Site #11

Akashi, Hyōgo, Japan
Eisai Trial Site #12

Kōtoku, Japan
Eisai Trial Site #13

Nagoya, Aichi-ken, Japan
Eisai Trial Site #14

Matsuya, Ehime, Japan
Eisai Trial Site #15

Yokohama, Kanaga, Japan
Eisai Trial Site #17

Suita, Osaka, Japan
Eisai Trial Site #18

Kashiwa, Chiba, Japan
Eisai Trial Site #19

Kitaadachi-gun, Saitama, Japan
Eisai Trial Site #2

Kashiwa, Chiba, Japan
Eisai Trial Site #3

Sendai, Miyagi, Japan
Eisai Trial Site #4

Kurume, Fukuoka, Japan
Eisai Trial Site #5

Osakasa, Osaka, Japan
Eisai Trial Site #6

Chuo Ku, Osaka, Japan
Eisai Trial Site #7

Sakai C, Osaka, Japan
Eisai Trial Site #8

Chuo Ku, Osaka, Japan
Eisai Trial Site #9

Wakayama, Wakaya, Japan

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