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Vaping may cause hidden gum damage, study suggests

NCT ID NCT07338318

Knowledge-focused Sponsor: Ankara Medipol University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether e-cigarettes cause hidden damage to gums, even when they appear healthy. Researchers measured certain chemicals in the fluid around the gums of 60 people: e-cigarette users, regular smokers, and non-smokers. The goal was to see if vaping triggers inflammation or tissue breakdown similar to smoking.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If this study finds that e-cigarettes cause hidden gum damage, it could help shape public health advice about their safety.
What could go wrong
This is a small, completed observational study, not a treatment trial. It only measures biomarkers, not actual disease, so the real-world impact is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

60 people

The number who actually took part.

Started

Apr 2025

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Systemically and periodontally healthy smokers, e-cigarette users, and non-smoking individuals over 18 years old.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * E-cigarette using, conventional smokers, non-smokers Exclusion Criteria: * Having active periodontal disease, systemic health problems

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Conditions

The condition(s) this trial relates to.

Smoking Vaping

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Periodontal health Smoking behaviors

Contacts and locations

Locations

  • Ankara Medipol Uni.

    Ankara, Ankara, 06570, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.