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Lymphoma drug duvelisib tested as Post-Transplant maintenance

NCT ID NCT04331119

First seen Jan 05, 2026 · Last updated Jun 19, 2026 · Updated 30 times

Summary

This Phase 2 trial tested the drug duvelisib (Copiktra) as a maintenance therapy after autologous stem cell transplant in 17 adults with T-cell lymphoma. The goal was to see if it is safe and improves progression-free survival. The study was terminated early, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Duvelisib (Copiktra)

What this could lead to

If successful, this could point toward a maintenance therapy that delays lymphoma progression after a stem cell transplant.

What could go wrong

This trial was terminated early with only 17 participants, so results are limited. Duvelisib may cause side effects like infections or liver issues, and it is not a cure.

Conditions

The condition(s) this trial relates to.

anaplastic large cell lymphoma angioimmunoblastic T-cell lymphoma peripheral T-cell lymphoma, not otherwise specified T-cell non-Hodgkin lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.