Can radiation after surgery stop Dupuytren's from coming back?
NCT ID NCT04122313
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study is testing whether adding radiation after surgery for Dupuytren's contracture leads to better hand function and fewer recurrences. Researchers will follow 50 patients who are already getting this treatment and ask them to fill out a questionnaire about their hand function. The goal is to see if doctors' impressions that this approach works can be backed up by scientific data.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could provide scientific evidence that radiation after surgery improves hand function and reduces recurrence for people with Dupuytren's disease.
- What could go wrong
- This is a small, observational study (50 people) that only measures patient-reported outcomes and recurrence rates. It cannot prove cause and effect, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2019
- Expected to finish
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Mar 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
English-speaking adults with a diagnosis of Dupuytren's disease whose have chosen to follow the current treatment pathway.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnoses of Dupuytren's disease * English-speaking Exclusion Criteria: \- Patients with Dupuytren's disease who are not currently seeking treatment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Minnesota
RECRUITINGMinneapolis, Minnesota, 55455, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Zapping away recurrence: radiation after Dupuytren's treatment put to the test
- New injection could unclench curved fingers
- Vitamin e gel could stop Dupuytren's before fingers curl
- Which treatment works best for Dupuytren's? major trial aims to find out
- Fat graft may keep Dupuytren's disease from returning after surgery
- New device may straighten bent fingers without surgery