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New hope for kids with stubborn hives: dupilumab study shows promise

NCT ID NCT05526521

First seen Nov 19, 2025 · Last updated May 21, 2026 · Updated 29 times

Summary

This study looked at how dupilumab works in children aged 2 to 12 with chronic spontaneous urticaria (CSU), a condition causing itchy hives and swelling that doesn't get better with standard allergy medicines. Fifteen children received dupilumab injections for 24 weeks, and researchers measured drug levels in the blood and monitored for side effects. The goal was to see if the drug is safe and how the body processes it in young children.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Boston Childrens Health Physicians Site Number : 8400017

    Hawthorne, New York, 10532, United States

  • Childrens Hospital Medical Center of Akron- Site Number : 8400020

    Akron, Ohio, 44308, United States

  • Cincinnati Children's Hospital Medical Center - PIN- Site Number : 8400001

    Cincinnati, Ohio, 45229-3026, United States

  • Columbia University Irving Medical Center Site Number : 8400003

    New York, New York, 10032, United States

  • Investigational Site Number : 1240001

    Montreal, Quebec, H4A 3J1, Canada

  • Investigational Site Number : 1240007

    Hamilton, Ontario, L8S1G5, Canada

  • Investigational Site Number : 1240009

    Calgary, Alberta, T2W 4X9, Canada

  • Investigational Site Number : 1240010

    Edmonton, Alberta, T5J 3S9, Canada

  • Investigational Site Number : 3920001

    Yokohama, Kanagawa, 232-8555, Japan

  • Investigational Site Number : 3920002

    Tsu, Mie-ken, 514-0125, Japan

  • Monroe Carell Jr. Childrens Hospital at Vanderbilt- Site Number : 8400005

    Nashville, Tennessee, 37232, United States

  • Pediatric Dermatology of Miami Site Number : 8400015

    Coral Gables, Florida, 33146, United States

  • Treasure Valley Medical Research Site Number : 8400019

    Boise, Idaho, 83706, United States

  • Vital Prospects Clinical Research Institute, P.C.- Site Number : 8400002

    Tulsa, Oklahoma, 74136, United States

  • Washington University School of Medicine- Site Number : 8400004

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.