Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New eye drop battle: can ectoin beat hyaluronic acid for dry eyes?

NCT ID NCT01684852

Symptom relief Sponsor: Bitop AG Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two types of eye drops—ectoin (BAT04) and hyaluronic acid—for treating dry eye disease. 64 adults with mild to moderate dry eye used the drops six times daily in both eyes for 28 days. The main goal was to see how well each drop improved tear film stability, measured by tear break-up time. Results were recorded at the end of the treatment period.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

64 people

The number who actually took part.

Start date

May 2012

Finished

Nov 2012

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

primary care clinic The selection of appropriate patients for the observational study is made by the individual physician in his treatment decisions in consultation with the individual patient

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female person aged 18 years * Demonstrated mild to moderate keratoconjunctivitis sicca ( "dry eye") * Acute symptoms of dry eye: DEWS 1-3 * tear break-up time TBUT \<10s * agreement to abide by the routinely provided doctor's appointment for follow-up (reflected in the planned visits of observation plan resist) Exclusion Criteria: * inflammation of the anterior segment or trauma * Contact lens wearers * Any disease that can, in the opinion of the treating physician to affect the outcome of the study. * Patients with known intolerance to one of the substances used * Surgical procedures to the eyes in the last 6 weeks before inclusion in the trial * patients with addictive disorders or substance abuse fallow in the past 12 months, as well as persons incapable of giving consent

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Dry eye syndromes are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

dry eye syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dry eye syndromes

Contacts and locations

Locations

  • Augenabteilung am St. Franziskus-Hospital Münster

    Münster, 48145, Germany

  • Augenklinik der LMU Klinikum der Universität Muenchen

    München, 80336, Germany

  • Augenklinik mit Poliklinik

    Erlangen, 91054, Germany

  • Dr. Insa Beddermann

    Duderstadt, 37115, Germany

  • Dr. Peter Otto

    Bad Liebenwerda, 04924, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.