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Cancer drug interaction study: will antibiotics or antifungals change the dose?

NCT ID NCT05372367

First seen Feb 03, 2026 · Last updated May 24, 2026 · Updated 20 times

Summary

This study looked at how a new cancer drug (BI 907828) interacts with two common medicines: rifampicin (an antibiotic) and itraconazole (an antifungal). 33 adults with advanced solid tumors took BI 907828 alone and then with each other drug. Researchers measured drug levels in the blood to see if the other medicines changed how much BI 907828 stayed in the body. This helps doctors understand safe dosing, but the study did not test if BI 907828 cures or controls cancer.

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Contacts and locations

Locations

  • CIO Clara Campal

    Madrid, 28050, Spain

  • Cliniques Universitaires Saint-Luc

    Brussels, 1200, Belgium

  • Fundación Jiménez Díaz

    Madrid, 28040, Spain

  • Hospital Quiron. I.C.U.

    Barcelona, 08023, Spain

  • Hospital Quirónsalud Madrid

    Madrid, 28223, Spain

  • Hospital Universitari Vall D Hebron

    Barcelona, 08035, Spain

  • Wilrijk - HOSP GZA (St-Augustinus)

    Wilrijk, 2610, Belgium

Conditions

Explore the condition pages connected to this study.