Cancer drug interaction study: what happens when you add antibiotics or antifungals?

NCT ID NCT05372367

First seen Feb 03, 2026 · Last updated May 13, 2026 · Updated 16 times

Summary

This study looked at how a new cancer drug (BI 907828) interacts with two common medicines: rifampicin (an antibiotic) and itraconazole (an antifungal). Thirty-three adults with advanced solid tumors who had run out of other options took part. Researchers measured drug levels in the blood to see if these other drugs changed how much BI 907828 stayed in the body. The goal was to understand safety and dosing, not to treat the cancer directly.

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Contacts and locations

Locations

  • CIO Clara Campal

    Madrid, 28050, Spain

  • Cliniques Universitaires Saint-Luc

    Brussels, 1200, Belgium

  • Fundación Jiménez Díaz

    Madrid, 28040, Spain

  • Hospital Quiron. I.C.U.

    Barcelona, 08023, Spain

  • Hospital Quirónsalud Madrid

    Madrid, 28223, Spain

  • Hospital Universitari Vall D Hebron

    Barcelona, 08035, Spain

  • Wilrijk - HOSP GZA (St-Augustinus)

    Wilrijk, 2610, Belgium

Conditions

Explore the condition pages connected to this study.