New pill cocktail may offer sleep apnea relief without a mask
NCT ID NCT06295562
First seen Jan 05, 2026 · Last updated Jun 22, 2026 · Updated 27 times
Summary
This completed phase 4 trial tested three different drug combinations to treat obstructive sleep apnea in adults. The study enrolled 45 participants and measured changes in breathing pauses during sleep. The goal was to see if these medications could improve sleep apnea by targeting the underlying causes, potentially offering an alternative to CPAP machines.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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China Medical University Hospital
Taichung, Taiwan
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
atomoxetine, oxybutynin, venlafaxine, trazodone
What this could lead to
If successful, these drug combinations could offer a new, non-device treatment option for obstructive sleep apnea.
What could go wrong
This is a small, early-phase trial with only 45 participants. The drugs may not work better than placebo, and side effects are possible.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.